Every so often someone impresses you with their ability to think outside the box and come up with an innovation that changes the world in some way. Stanford bioengineer, Manu Prakash did just that. He created a paper-based centrifuge that can spin biological samples fast enough to help diagnose infections like malaria and HIV. It’s called Paperfuge, fits in a pocket, doesn’t need electricity to run, and costs less than 25 cents to make. Prakash applies an approach called “frugal science” to drive innovation. He also developed a paper microscope based on origami. Read more about this life-changing tool.